Invokana Lawsuits | Invokana Side Effects | Invokana Side Effects Lawyers
Invokana is supposed to help lower blood sugar with help from the kidneys through the process of urination. Specifically, it is supposed to work by blocking sugar from reabsorbing into the blood stream, which should increase the amount of sugar that is excreted through urination. The increased sugar excretion through urination is thought to help lower blood sugar levels. According to Janssen’s Invokana website, “INVOKANA® works with your kidneys to help you lose some sugar—about 100 grams a day—through the process of urination.” However, Invokana and and various other SGLT2 inhibitors are now linked to extremely serious medical conditions, amputations, and even death.
According to Janssen’s Invokana website, “INVOKANA® is a prescription medicine used along with diet and exercise to lower blood sugar in adults with type 2 diabetes. INVOKANA® is not for people with type 1 diabetes or with diabetic ketoacidosis (increased ketones in blood or urine). It is not known if INVOKANA® is safe and effective in children under 18 years of age.”
Additionally, the FDA provides the following facts about Invokana (canagliflozin):
Invokana: Canagliflozin is a prescription medicine that is used with diet and exercise to lower blood sugar in adults with type 2 diabetes. It belongs to a class of drugs called sodium-glucose cotransporter-2 (SGLT2) inhibitors.
Invokana: Canagliflozin is available as a single-ingredient product under the brand name Invokana, and also in combination with the diabetes medicine metformin under the brand names Invokamet and Invokamet XR.
Invokana: Canagliflozin lowers blood sugar by causing the kidneys to remove sugar from the body through the urine.
Within two years of FDA approval, government agencies across the world have issued a series of warnings and advisories about the risks, complications, and side effects associated with Invokana. More recently, the FDA now requires Invokana to have a “Black Box” warning label. This is the strictest warning label associated with a product, frequently assigned prior to a product being removed from the marketplace. The FDA has enforced this “Black Box” warning label due to dangerous and shocking findings in additional studies and testing.
One of Invokana’s most widely studied complications is linked to diabetic ketoacidosis (DKA). Study after study have shown that patients taking Invokana may develop DKA. Diabetic Ketoacidosis is a result of overly acidic blood: too much acid in the blood. Some cases of DKA can result in coma or death.
The FDA mandated the addition of a warning to the Invokana label for the increased risk of diabetic ketoacidosis. These labels warn patients to seek immediate medical attention if they experience symptoms of DKA, such as:
The FDA has released multiple studies, warnings, and alerts since Invokana was approved and released on the marketplace. The recent timeline of actions and studies taken by the FDA are as follows:
May 2015: FDA warned that Invokana may lead to diabetic ketoacidosis, a serious condition that can require hospitalization.
May 2016: FDA issued a Drug Safety Communication warning the public about “an ongoing clinical trial that found an increase in leg and foot amputations, mostly affecting the toes,” in patients who had taken Invokana.
June 2016: FDA further strengthened the warnings for Invokana “to include information about acute kidney injury.” The FDA is requesting patients and medical professionals to monitor and report side effects to the FDA MedWatch program.
Late 2016: FDA is “evaluating the need for regulatory action” after detecting serious risk of acute pancreatitis via adverse events reported to the FDA, as Invokana patients have developed this condition. Previous studies warned that drug-induced pancreatitis (DIP) “may easily be overlooked” in patients taking Invokana.
May 2017: FDA determined that “Based on new data from two large clinical trials . . . canagliflozin (Invokana, Invokamet, Invokamet XR) causes an increased (double) risk of leg and foot amputations. The FDA now requires the most prominent Boxed Warning, “Black Box” to be added to the drug labels.
If you or a loved one have experienced any of these side effects, complications or conditions after taking Invokana, please Contact Peiffer Wolf Carr & Kane as soon as possible for a FREE Consultation by filling out a Contact Form or by calling 833-INVOKANA. Moreover, if a loved one has died from complications while taking Invokana, you should reach out to us so we can examine your case. You may be entitled to compensation for your medical expenses, lost wages, pain and suffering, and other costs.
If you or a loved one has been injured after taking Invokana, the Invokana lawyers at Peiffer Wolf Carr & Kane can walk with you through this fight against Janssen’s Invokana. Contact us today for a FREE Consultation by filling out an online Contact Form or by calling 833-INVOKANA.